- Black Coffee
- original.
- First performance: 8 December 1930, at Embassy Theatre
- Publish: Ashley, 1934
- Novelised by Charles Osborne in 1997 as Black Coffee
- Ten Little Niggers
- based on the 1939 novel Ten Little Niggers (And Then There Were None)
- First performance: 17 October 1943, at St James's Theatre
- Publish: Samuel French, 1944
- Appointment with Death
- based on the 1938 novel Appointment with Death
- First performance: 31 March 1945, at Piccadilly Theatre
- Publish: Samuel French, 1945
- Murder on the Nile
- based on the 1937 novel Death on the Nile
- First performance: 1945, at Wimbledon Theatre
- Publish: Samuel French, 1945
- The Hollow
- based on the 1946 novel The Hollow
- First performance: 7 June 1951, at Fortune Theatre
- Publish: Samuel French, 1952
- The Mousetrap
- based on the short story Three Blind Mice
- First performance: 25 November 1952, at Ambassadors Theatre
- Publish: Samuel French, 1954
- Witness for the Prosecution
- based on the short story The Witness for the Prosecution
- First performance: 28 October 1953, at Winter Garden Theatre
- Publish: Samuel French, 1954
- Spider's Web
- original.
- First performance: 14 December 1954, at Savoy Theatre
- Publish: Samuel French, 1957
- Novelised by Charles Osborne in 2000 as Spider's Web
- Towards Zero
- with Gerald Verner, based on the 1946 novel Towards Zero
- First performance: 4 September 1956, at St James's Theatre
- Publish: Samuel French, 1957
- Verdict
- original.
- First performance: 22 May 1958, at Strand Theatre
- Publish: Samuel French, 1958
- The Unexpected Guest
- original.
- First performance: 12 August 1958, at Duchess Theatre
- Publish: Samuel French, 1958
- Novelised by Charles Osborne in 1999 as The Unexpected Guest
- Go Back for Murder
- based on the 1946 novel Five Little Pigs
- First performance: 23 March 1960, at Duchess Theatre
- Publish: Samuel French, 1960
- Rule of Three
- original.
- First performance: 20 December 1962, at Duchess Theatre
- Publish: Samuel French, 1963
- Fiddlers Three
- original.
- First performance: 7 June 1971, at Kings Theatre, Southsea
- Akhnaton
- original.
- Publish: Collins, 1973
- Chimneys
- based on the 1925 novel The Secret of Chimneys
- First performance: 1 June 2006, at Pitlochry Festival Theatre Company
- unpublished.